VAT1L antibody (AA 321-419) (Biotin)

Catalog No. ABIN1389451

This Rabbit Polyclonal antibody specifically detects VAT1L in WB, ELISA, IHC (fro) and IHC (p). It exhibits reactivity toward Rat.

Quick Overview for VAT1L antibody (AA 321-419) (Biotin) (ABIN1389451)

Target: VAT1L (Vesicle Amine Transport 1-Like (VAT1L))

Reactivity: Rat

Host: Rabbit

Clonality: Polyclonal

Conjugate: This VAT1L antibody is conjugated to Biotin

Application: Western Blotting (WB), ELISA, Immunohistochemistry (Frozen Sections) (IHC (fro)), Immunohistochemistry (Paraffin-embedded Sections) (IHC (p))

Product Details anti-VAT1L Antibody (Biotin)

Binding Specificity: AA 321-419

Cross-Reactivity: Rat

Predicted Reactivity: Human,Mouse,Dog,Cow,Pig

Purification: Purified by Protein A.

Immunogen: KLH conjugated synthetic peptide derived from human VAT1L/KIAA1576

Isotype: IgG

Application Details

Application Notes: WB 1:300-5000
IHC-P 1:200-400
IHC-F 1:100-500

Restrictions: For Research Use only

Handling

Format: Liquid

Concentration: 1 μg/μL

Buffer: Aqueous buffered solution containing 0.01M TBS ( pH 7.4) with 1 % BSA, 0.03 % Proclin300 and 50 % Glycerol.

Preservative: ProClin

Precaution of Use: This product contains ProClin: a POISONOUS AND HAZARDOUS SUBSTANCE, which should be handled by trained staff only.

Storage: -20 °C

Storage Comment: Store at -20°C for 12 months.

Expiry Date: 12 months

Target Details for VAT1L

Target: VAT1L (Vesicle Amine Transport 1-Like (VAT1L))

Alternative Name: VAT1L/KIAA1576

Background:

Synonyms: Probable oxidoreductase KIAA1576, Synaptic vesicle membrane protein VAT 1 homolog like, Synaptic vesicle membrane protein VAT-1 homolog-like, VAT 1L, VAT1L, VAT1L_HUMAN, Vesicle amine transport protein 1 homolog T. calornica like.

Background: Chromosome 16 encodes over 900 genes in approximately 90 million base pairs, makes up nearly 3 % of human cellular DNA and is associated with a variety of genetic disorders. The GAN gene is located on chromosome 16 and, with mutation, may lead to giant axonal neuropathy, a nervous system disorder characterized by increasing malfunction with growth. The rare disorder Rubinstein-Taybi syndrome is also associated with chromosome 16, though through the CREBBP gene which encodes a critical CREB binding protein. Signs of Rubinstein-Taybi include mental retardation and predisposition to tumor growth and white blood cell neoplasias. Crohn's disease is a gastrointestinal inflammatory condition associated with chromosome 16 through the NOD2 gene. An association with systemic lupus erythematosis and a number of other autoimmune disorders with the pericentromeric region of chromosome 16 has led to the identification of SLC5A11 as a potential autoimmune modifier. The KIAA1576 gene product has been provisionally designated KIAA1576 pending further characterization.

Gene ID: 3384